N- METHYL 4 CHLORO PIPERIDINE BASE

Name	N-Methyl-4-chloro-piperidine
Synonyms	N-Methyl-4-chloro 4-chloropiperidin-1-amine N-Methyl-4-Chloropiperdine 4-Chloro-1-methylpiperidine 4-chloro-1-methyl-piperidin 4-CHLORO-1-METHYLPIPERIDINE 4-Chloro-N-methylpiperidine 4-Chloro-1-Methylpiperidine N-Methyl-4-chloro piperidine N-METHYL-4-CHLORO PIPERIDINE N-Methyl-4-chloro-piperidine 4-CHLORO-N-METHYL PIPERIDINE 4-chloro-N-Methyl piperidine 1-METHYL-4-CHLORO-PIPERIDINE 4-chloro-1-methylpiperidinium Piperidine, 4-chloro-1-methyl- N- METHYL 4 CHLORO PIPERIDINE BASE (2Z)-2-(1-amino-3-methyl-2-benzimidazolylidene)-2-cyanoacetic acid ethyl ester
CAS	5570-77-4
EINECS	226-942-4
InChI	InChI=1/C5H11ClN2/c6-5-1-3-8(7)4-2-5/h5H,1-4,7H2
InChIKey	MYGXGCCFTPKWIH-UHFFFAOYSA-N

Molecular Formula	C6H12ClN
Molar Mass	133.62
Density	1.02
Melting Point	160-165°C
Boling Point	162°C(lit.)
Flash Point	48 °C
Water Solubility	1.533g/L at 29℃
Vapor Presure	3.493hPa at 25℃
Appearance	clear liquid to slightly cloudy liquid
Color	Colorless to Light yellow to Light orange
pKa	7.88±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.4670-1.4710
Physical and Chemical Properties	Boiling point 160-162 °c; 47-48 °c/1.3kPa.
Use	Important pharmaceutical intermediates for the synthesis of antihistamines such as ketotifen, thiacridine, loratadine, etc

Risk Codes	R10 - Flammable R34 - Causes burns R36/38 - Irritating to eyes and skin.
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S16 - Keep away from sources of ignition.
UN IDs	1993
HS Code	29333990
Hazard Class	3
Packing Group	III

LogP	1.318 at 25℃
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Use	intermediates of thiacridine, ketotifen, cyproheptadine hydrochloride. important pharmaceutical intermediates for the synthesis of antihistamines such as ketotifen, thiacridine, loratadine, etc.
production method	1-methyl-4-piperidone can be used for catalytic hydrogenation, 1-methyl-4-hydroxypiperidine was formed and then thionyl chloride was used to prepare the product.

Last Update：2024-04-09 19:05:07

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Product Name: N-Methyl-4-chloro-piperidine Request for quotation
CAS: 5570-77-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756

Spot supply

Product Name: Loratadine Impurity 31 Visit Supplier Webpage Request for quotation
CAS: 5570-77-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052

Wechat: 15671228036

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N- METHYL 4 CHLORO PIPERIDINE BASE

N- METHYL 4 CHLORO PIPERIDINE BASE Request for Quotation